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Dyazide (hydrochlorothiazide and triamterene) should be used with caution in patients with a history of renal stones. Impaired Renal Function : dyazide (hydrochlorothiazide and triamterene) is contraindicated in patients with anuria, acute and chronic renal insufficiency or significant renal impairment. Following oral administration of multiple daily doses of 600 mg (1 tablet/day) to asymptomatic HIV-positive adults, mean maximum concentration in peripheral leukocytes was 252 g/mL (49). In this trial, 13,388 women of at least 35 years of age were randomized to receive either Tamoxifen or placebo for five years. No glucocorticoid or mineralocorticoid replacement therapy is necessary with anastrozole. There are, however, no adequate prescription and well-controlled studies in pregnant women. The trial closed in 1997 due to the large number of dropouts during the first year of treatment (26). The FDA approved in December 1965. Hydrochlorothiazide is used for long-term treatment. 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